Q. A 25-year old woman has presented to the clinic for assessment. She has a past medical history of palpitations and is suspected to have congenital long QT syndrome from evidence of her ECG findings. Which one of these drugs should be avoided? A. Amoxycillin B. Thyroxine C. Sertraline D. Paracetamol Answer: C - Sertraline Explanation: Common drugs which cause long QT syndrome are: Tricyclic antidepressants ( e.g.sertraline) Antiarrhythmics: Quinidine Disopyramide Procainamide Amiodarone Sotalol Antipsychotics: Haloperidol and thioridazine Cisapride Antimalarials: Halofantrine Terfinadine
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