Skip to main content

MCQ 45: Number needed to treat

Q. A trial assessed a statin tablet compared to placebo for stroke prevention over 1 year. There were 10% of patients developing stroke in the group taking a tablet and 20% in the carotid endarterectomy group developing a stroke over the 1 year.What is the number needed to treat over 1 year to prevent 1 death?  
Options:
A.1
B. 10
C. 100
D.1000

Answer: B. 10

Explanation:

Number needed to treat (NNT) is defined as number of patients being given treatment for prevention of one death.

Number need to treat: 1/Absolute risk reduction

Stroke in patients taking tablet: 10%= 0.1
Stroke in patients undergoing endarterectomy: 20%= 0.2
Absolute risk reduction: 0.2-0.1= 0.1
So, Number needed to treat to save one life: 1/0.1= 10  

Comments

Popular posts from this blog

ECG Spotter

What is the diagnosis? Click the button below to view answer: Show Answer

MCQ

 Cardiology MCQ Q. Which of the following leads is not an inferior lead in ECG? A. Lead II B. Lead III C. Lead aVF D. Lead aVR Click the button below to view answer Show answer Correct answer is option D. Lead aVR

Coronary artery perforation

  Management of coronary artery perforation 1.       Balloon inflation for occlusion of vessel 2.       General circulatory support → Intravenous fluids and vasopressors 3.       Urgent pericardiocentesis if cardiac tamponade (may consider autotransfusion) 4.       Call anaesthetist and inform surgeons. Repeat angiogram ↓ Extravasation settled → Yes → Monitor patient ↓ No #        Large vessel perforation 1.       Prolonged balloon inflation 2.       Covered stent placement #        Small distal vessel perforation 1.       Embolization (fat, coils, thrombin, balloon fragment) 2.       Covered stent in main vessel over perforated branch origin