Marfan's syndrome- Diagnostic criteria (15)

MAJOR

1) Dilatation of ascending aorta, with or without AR, involving at least the sinuses of valsalva

2) Dissection of the descending aorta

MINOR

1) Dilatation or dissection of the descending thoracic or abdominal aorta before 50 years of age

2) Dilatation of the MPA before 40 years of age

3) Mitral valve prolapse with or without MR

4) Calcification of the mitral annulus before 40 years of age

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ECG Spotter

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Peripartum Cardiomyopathy

Peripartum Cardiomyopathy (PPCM) • Usually develops in last month of pregnancy or first 5 months post-delivery. • Presents as heart failure with reduced ejection fraction (dilated cardiomyopathy) ↳ LV EF < 45% • PPCM is a diagnosis of exclusion. • Risk factors → 1- History of Hypertension, Pre-eclampsia 2- Black women • Incidence → 1 in 2000 live births. • Management → 1. Guideline directed medical therapy for HF- Beta-blockers Hydralazine plus isosorbide dinitrate Diuretics 2. Bromocriptine 3. Low threshold for anticoagulation 4. ...

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